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KMID : 1103720210820030756
Journal of the Korean Society of Radiology
2021 Volume.82 No. 3 p.756 ~ p.763
Early and Atypical Radiologic Presentations of Pulmonary Langerhans Cell Histiocytosis: A Report of Two Cases
Ryu Kyung-Hwa

Nam Bo-Da
Hwang Jung-Hwa
Kim Dong-Won
Park Young-Woo
Oh Hong-Chul
Park Soo-Bin
Abstract
Pulmonary Langerhans cell histiocytosis (PLCH) is a rare, multi-systemic disease primarily affecting young male adults with a history of smoking. The two patients with PLCH in our report showed relatively early and atypical radiologic presentations at initial evaluation. On chest CT, PLCH presents variable radiologic features depending on the evolutional stage of the disease. Atypical CT features of PLCH may render precise radiologic diagnosis difficult and usually require lung biopsy for a confirmation of the diagnosis. Our case review is aimed at raising the awareness of radiologists on the atypical CT features of PLCH, to help make accurate radiologic diagnosis and prevent unnecessary and invasive diagnostic procedures.
KEYWORD
Histiocytosis, Langerhans-Cell, Lung, Tomography, X-Ray Computed, Radiography
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